Somehow I just ran into this thread although it has been going on for several months. It is right up my alley. As a physician for many years, I've had access to the best information, have tried to use it personally and have encouraged anyone who would listen.

It all boils down to diet and exercise. Find whatever works for you, something you enjoy, and make it part of your life style. People lose hundreds of pounds and end up weighing the same. They jump from one exercise fad to another with no permanent gain.

Find a sensible diet and exercise plan. Stick to it! You may very well find you can reduce or eliminate medications. If enough of the population would do this we could save this country perhaps billions in health care cost.